The
construction of neural circuits in cortical structures involves complex
developmental processes, including sequential generation of different
neuron categories, their homing in precise cortical layers and the
formation of highly patterned local and distant connections. All these
features emerge from largely unknown interactions between
genetically-determined mechanisms and influences from the external
world. The symposium is devoted at discussing new insights in some
specific aspects of cortical development, including gene expression
patterns that define specific neuron phenotypes and populations,
cellular interactions that determine the morpho-functional identity of
cortical areas or nodules, integration of neurons in cortical layers
and circuits, wiring of long-distance projections and local inhibitory
connections. In particular, we aim at bringing together and compare
complementary experiences drawn from the study of the ontogenesis of
major cortical structures in the mammalian brain, the cerebral and
cerebellar cortex. |
- Alessandro Vercelli:
Development and plasticity of cortical pyramidal neurons.
- Zoltan Molnar:
Towards the classification of projection neurons in layer V and
subplate.
- Marion Wassef: Cell
interactions involved in the development of functional modules in the
cerebral and cerebellar cortex.
- Ferdinando Rossi:
Specification and integration of inhibitory interneurons in the
cerebellar cortex.
|