N.M. Toan, D. marenduzzo, P.R. Cook and C. Micheletti
Depletion effects and loop formation in self-avoiding polymers
Phys. Rev. Lett. 97, art. No. 178302 (2006)
Link to online article.
Langevin dynamics is employed to study the looping kinetics of
self-avoiding polymers both in ideal and crowded solutions. A rich
kinetics results from the competition of two crowding-induced effects:
the depletion attraction and the enhanced viscous friction. For short
chains, the enhanced friction slows down looping, while for longer
chains, the depletion attraction renders it more frequent and
persistent. We discuss the possible relevance of the findings for
chromatin looping in living cells.